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Streamline Genomics

Senior Infrastructure Engineer

Remote / Full Time

March 1

At Streamline Genomics, we’re building the software infrastructure for the future of medical genomics. We directly serve medical oncologists by providing them the tools to effectively extract the insight they need from huge amounts of genomic data. Our common goal is for every cancer patient to receive the best possible treatment tailored to their genetics. And we want you to be part of our story.

You will be joining an interdisciplinary team of engineers, geneticists, and data scientists whose mission is to remove the technological barriers to adoption of medical genomics. It’s still the early days for us and there are plenty of high-impact, challenging problems to solve. 

We’re a remote-first company with a timezone preference for North America. With that in mind, we welcome applications from around the world.

All positions include benefits, participation in the company’s equity incentive plan and total compensation package competitive for an early-stage startup.

You will:

  • Design, develop, and own key pieces of our cloud infrastructure and CI/CD pipelines.
  • Advocate for and lead improvements to product quality, security, and performance.
  • Anticipate and plan for growth by proactively identifying architectural weaknesses.
  • Make impactful decisions about systems and security — their edge cases, failure modes, and life cycles.
  • Uphold and improve our engineering standards, tooling and processes.

You may be a good fit if you:

  • have 4+ yrs of relevant engineering experience.
  • thrive in an interdisciplinary environment, working with stakeholders across different areas of expertise.
  • have experience planning and executing large projects involving multiple systems, technologies, and teams.
  • can make informed, pragmatic decisions about different concurrency models (multithreading, asynchronous programming, etc.)
  • know your way around a Unix shell.
  • take delight in anticipating how systems fail and how to fix them.
  • have a solid understanding of Linux containers and at least one of the leading cloud providers (AWS, GCP, Azure)
  • have practical experience with infrastructure-as-code (e.g. Terraform) and configuration management tools (e.g. Ansible, Chef).
  • have experience optimizing the reliability and security of distributed systems
  • can debug distributed systems across all layers of the stack, from cloud provider APIs all the way down to the OS level.
  • have experience owning significant pieces of cloud infrastructure.
  • have a proactive attitude. When something is broken, you can’t help but fix it.
  • have a metrics-driven approach and can make informed decisions using data.
  • have a learning mindset, regardless of level or experience.
  • are an excellent communicator. We are a distributed team; clear written and oral communication is a must.
  • are self-driven. Our business is growing and changing rapidly. We are looking for engineers who love taking initiative and seeing things through to completion.

You might work on:

  • extending our cloud infrastructure to a multi-datacenter setting to support clients in different geographies and jurisdictions.
  • optimizing the resource usage of our batch processing pipelines.
  • continuous integration and deployment of our bioinformatics pipelines.
  • monitoring systems for our production servers.
  • optimizing the SLIs of our production servers, formulate and manage our SLOs.
  • developing security best practices for the entire engineering team.

Areas for growth:

  • Leadership: for those interested in engineering leadership we offer the option of becoming a team lead.
  • Architecture: we encourage our engineers to build expertise in systems they work with and thoughtfully guide their evolution.
  • Learning: our success depends on our ability to be continuously learning. We encourage and enable our engineers to grow their skills through books, courses, and conferences.
  • Open source: we love and heavily rely on open source! We provide opportunities for publishing and presenting internal software tools that could benefit the broader community.


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